Research & Biophotonics Lasers – Lasers for Research & Biophotonics Markets

What are Reasearch & Biophotonics Lasers?

Research & Biophotonics Lasers play a crucial role in the field of scientific research and biophotonics, providing scientists and researchers with powerful tools to investigate, analyze, and manipulate various aspects of light-matter interactions. These advanced laser systems offer precise control and high energy output, enabling a wide range of applications in imaging, spectroscopy, molecular analysis, and more. By harnessing the unique properties of laser light, researchers can delve into the mysteries of the microscopic world, unravel complex biological processes, and uncover valuable insights that contribute to advancements in various scientific disciplines.

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As research and the biosciences have evolved and diversified over the past 50 years so have the laser application and technologies used within it.  Because of their early adoption of laser technology, the medical, biomedical, and life sciences have made rapid progress, including the complete mapping of the human genome.

On the research side of things, the most popular life science laser application is fluorescence.  Fluorescence has become so popular that it has been subdivided into a wide range of different applications, each leading to their own field of study.  This includes but is not limited to flow cytometry, DNA sequencing, confocal fluorescence microscopy, and fluorescence lifetime imaging microscopy.  More recently ultra-fast lasers have become more prevalent in fluorescence microscopy enabling multiphoton excitation allowing users to create high-resolution fluorescence images of living cells, without damaging the cells in the process.


To learn more about the various research & biophotonics laser applications and the recommended laser sources, click on any of the application groups listed below, or click the ‘Get Answers’ button to contact us for quick support and answers to your questions!

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Research & Biophotonics Laser Applications

Here are some of the key applications we support in the Research & Biophotonics Markets – Click an Application Group to learn more:

Imaging & Analysis
  • Fluorescence Lifetime
  • Maldi-ToF
  • Particle Image Velocimetry (PIV)
Spectroscopy & Analysis
  • Laser Induced Breakdown Spectroscopy (LIBS)
  • Non-linear Spectroscopy
  • Raman Spectroscopy
Measurement & Analysis
  • Dynamic Light Scattering
  • Infrared Absorption Spectroscopy
  • Laser Doppler Velocimetry
  • DIAL LIDAR
  • Photoluminescence
Molecular Manipulation & Analysis
  • Confocal Fluorescence Microscopy
  • DNA Sequencing
  • Flow Cytometry
  • Optogenetics
Pump Lasers
  • Pump Lasers – Fiber & DPSS
Seed Lasers
  • Seed Lasers – Fiber & DPSS
Optical Amplifiers
  • Fiber & DPSS

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Matchbox Series

R1Z4-Matchbox Laser

The Matchbox series offers excellent performance and reliability in the “World’s Smallest” ultra-compact, all-in-one, integrated laser head. They can operate on a 5V power supply while maintaining low noise operation. The monolithic design of the Matchbox Series laser includes thermally stabilized optics in a hermetically sealed housing, ensuring reliable and maintenance-free operation. This series is available in wavelengths from 405 nm thru 1064nm, with options for collimated beam or fiber-coupled output, and single-mode and multimode versions.

CEUV Series

R0Z2-Image-Compact-Efficient-UV-LaserThe CEUV series is a commercial line of compact and efficient DPSS laser sources, capable of operating over a wide range of pulsing conditions (duty-cycle and PRF), in a low SWaP package, with average power up to ≈5W @ 266nm, 10W @ 355nm or 532nm, 20W @ 1064nm. This series of DPSS lasers provides a combination of compact, efficient, and high-power performance in a rugged design suitable for harsh environments and airborne applications. The design has been tested in brassboard hardware and a prototype is being developed.

ER Series

The ER Series offers an ultra-compact, ultra-low SWaP, and efficient solution for those seeking high-quality diode-pumped lasers for lightweight, handheld, and portable laser range finding applications. These lasers operate at an “eye-safe” wavelength of 1.5 µm and deliver high pulse energy up to 200 µJ with a 4 ns pulse width and repetition rates from single-shot up to 10Hz with optional burst mode. The ER Series is designed with a focus on high pulse energy, short pulse width, efficient operation, and long lifetime reliability with a 10M shot lifetime rating.

Halite 2 Series

The Halite 2 series is a compact, single-box, all-fiber femtosecond laser designed to meet the most demanding applications in neuroscience, biophotonics, microscopy, and engineering. With pulses as short as <250 fs (< 100 fs op.), average power over 2 W at 1030 nm, and the option of second harmonic at 515 nm, it is an irreplaceable tool in every lab that needs a reliable, turn-key, ultrafast light source. Thanks to its unique construction and SESAM-free technology, it is a cost-effective solution that provides high pulse energy (over 100 nJ), excellent beam quality, and easy integration.

Harmony Series

The Harmony series is a single-box optical parametric amplifier that converts ultrafast pulses from Ytterbium-based lasers into broadly tunable pulses with wavelengths ranging from 210 nm to > 10 µm. With intuitive, user-friendly PC software, an integrated mini spectrometer enables automatic tuning from 315 to 2600 nm. Designed to operate from a single pulse up to 300kHz rep. rate with pump pulse energy from 30 µJ to 200 µJ, Harmony is compatible with all Ytterbium-based femtosecond lasers, but it works best with the Jasper series: the Jasper X0 & Jasper Flex lasers featuring exceptional beam-pointing stability.

LGK Series

The LGK series of HeNe laser modules boast an excellent TEM00 beam, robust mechanical design, a long service life of up to 30,000 hours, and are available in 543, 594, and 632.8nm wavelengths, with output powers up to 20mW. Choose between standard and customized models, with options for single or multimode, random or linear polarization, Brewster window tubes, and fiber coupling. Designed for long life, low noise, and high stability, with many customization options, these HeNe lasers are perfect for spectroscopy, interferometry, holography, and more!

HL Series

TG420

The HL Series offers versatile and high-quality laser diode products in a variety of wavelengths and high-power options, ideal for direct imaging, industrial, and bio/medical applications. These reliable, efficient, and compact diodes come in TO-Can packages, making them perfect for OEM integration. Additionally, they operate with TE mode oscillation and are RoHS compliant, ensuring safe use. Choose the HL Series for quality, reliability, and performance in laser diodes. 

Jasper Series

The Jasper series is a diverse set of high-performance femtosecond fiber lasers providing different solutions based on a standard technology. The series includes the high-power Jasper X0 (200 µJ pulse energy / 60 W average power), the compact Jasper Micro (5 µJ pulse energy / 7 W average power) in a space-saving design, and the Jasper Flex for microprocessing (30 µJ pulse energy). Each model provides a fast warm-up time, long-term stability, and hands-free operation. Whether you need high power, compactness, or specific processing capabilities, the Jasper series has a solution.

KAUKAS Series

The KAUKAS series is a compact, low-SWaP line of 1.54µm “eye-safe” Er:glass lasers. These nanosecond pulsed lasers feature a compact design that makes them suitable for integration into handheld, portable devices. The lasers deliver high pulse energy, repetition rates up to 5Hz, less than 3% energy stability, and a high-quality TEM00 beam. With configurable and customizable options, these features make the KAUKAS series a versatile choice for various applications such as LIDAR & laser ranging, LIBS, metrology, and instrumentation.

Lampo Series

Image of a modern OEM laser housing made of high-grade aluminum, long silver rectangle body with fan slits, output window and stickersThe Lampo Series is a line of compact ultrafast lasers that deliver megawatt-level ps laser pulses at a selectable PRR from 50 kHz to 4 MHz. Available in IR (1064 nm), SHG (532 nm), and Deep-UV (266 nm) versions, the series offers pulse durations < 70 ps and average power up to 20W, 10W, and 1.5W respectively. With pulse energy up to 250uJ, 150uJ, and 30uJ, these lasers are ideal for a wide range of scientific, industrial, defense, medical, biological, and LIDAR applications. Built into a rugged, air-cooled single-unit laser head, these lasers are easy to operate and integrate, making them a valuable tool for sophisticated laser systems and lab applications.

LaserBoxx Low Noise Series

The LaserBoxx Low Noise series of CW diode laser modules & DPSS lasers offer wavelengths from 375 to 1064nm, output powers up to 500 mW, and OEM & plug-&-play modules. These rugged, compact & highly customizable lasers also offer excellent beam quality & stability, modulation capabilities, ultra-low noise output & options for SM, MM, and PM fiber coupling. Our dedicated control software, USB and RS232 interfaces, and external controller with power display make integration, operation, and remote diagnostics a breeze.

LaserBoxx HPE Series

LBX-488

The LaserBoxx HPE Series is a highly versatile and customizable laser diode module series that offers superior performance and reliability in a compact, driver-integrated laser head. With a wide range of wavelengths from the UV to the NIR, this series provides high-power output, removable MM fiber coupling options & dedicated control software with USB and RS232 interfaces, as well as an external controller with power display, ensuring easy integration and precise power and modulation control.

LaserBoxx SLM Series

The LaserBoxx-SLM series of SLM CW DPSS & diode laser modules are available in wavelengths from 532-1064 nm, delivering ultra-narrow line widths with excellent temperature stability and low noise current. Embedded firmware locks the laser on the same mode at each startup. This customizable, compact laser module is available in turn-key or OEM versions, with GUI for remote operation & diagnostics via USB, RS232, or direct I/O interface, with modulation capabilities and adjustable power options.

LDX Series

The LDX Series of made-in-the-US, high-power, multimode laser diodes provide wavelengths from 400nm – 1900nm, a wide range of output powers and package types, as well as completely customized solutions. We have been offering these high-quality laser diodes for over 25 years. The performance, reliability, and lifetimes are time tested, and if for some reason there is an issue, we will make it right. 

LGR Series

The LGR series of HeNe laser replacement tubes provide unparalleled performance for a wide range of applications, have a robust mechanical design, excellent beam quality, and a long service life of up to 30,000 hours. Standard and customized models are available at 632.8nm with output powers up to 10 mW and options for side line suppression, polarization switching elimination, two longitudinal modes, magnetic field stability up to 3 G, and split frequency versions. These advanced options provide versatility for a range of sophisticated and high-precision scientific applications.

LXCc Series

R2Z3-L4Cc Combiner

The LXCc series is a range of compact, highly customizable, and flexible all-in-one laser combiners that provide the widest variety of wavelength options, up to 7 different laser lines (up to 500 mW output power per line), direct modulation on every source, SLM capabilities, proven long-term stability, and many other advanced features. The turnkey or OEM versions allow a large choice of lasers from 375nm up to 1064nm. The extension module provides the ultimate level of flexibility with options for up to 4 optical fiber outputs, AOTF modulator, motorized ND filter, integrated fast switching output ports for FRAP, or adjustable split power for light-sheet microscopy. 

MicroMake Series

The MicroMake Series is a fully-integrated, compact, sub-ns DPSS laser micromachining system for high precision and resolution applications. A flexible platform at 532 & 266 nm, with >40 kW of peak power and processing speeds up to 100mm/second, the system includes all the needed devices for direct laser micro-processing in a single, monolithic, air-cooled configuration. Equipped with a live microscope, alignments and in-process quality checks are a breeze. All these features perfectly suit various materials utilized in microelectronic circuits, displays fabrication and correction, biomedical device machining and optical substrates microprocessing.

Nps Series

image of a sleek tunable laser platform

The NPS series of ultrafast lasers is the ultimate solution for OEM integrators and researchers working with nonlinear optics applications like OPO pumping and narrowband Raman spectroscopy. The NPS series boasts remarkable features such as up to 10W average output power, <7ps pulse width, and a 40MHz repetition rate. The transform-limited operation, with a spectral width of <0.3nm, and accurate central wavelengths make these lasers a suitable candidate for highly efficient amplification by Nd-doped DPSS amplifiers.

Onda Series

Onda 532nm: 532nm High Energy Laser

The Onda series is a DPSS nanosecond OEM laser platform designed for high-end applications requiring excellent beam quality and high peak power in materials such as metals, glass, plastics, and various delicate and hard materials. This compact and easy to use laser series is available in wavelengths of 266, 355, 532, and 1064nm, with an extended operating temperature range and superior performance to cost ratio. The Onda seriesinternal optical layout and accurate temperature management enable high output energies without compromising the lifetime of the THG and FHG stages. 

One Series

One-1030-100: 1030nm Miniature Q-Switched Laser

The One Series is a versatile, passive q-switch laser series designed for OEM integrators and application specialists working with industrial and portable applications like materials processing and airborne LIDAR. With its compact size, configurable options such as fixed or external trig. repetition rate, and high energy (up to 100µJ) or high average power (up to 3W) versions, this 1030nm series offers exceptional performance for a range of applications.

PowerMir Series

mirSense Product Family

The PowerMir series is a line of high-power, pulsed Quantum Cascade Lasers based on proprietary technology, available in turnkey benchtop systems, OEM driver + laser module, or HHL package. Our lasers operate in Quasi-Continuous Wave (QCW) mode, enhancing wall-plug efficiency and thermal dissipation. The PowerMir series is ITAR-free, featuring high-powered diodes that emit in the primary atmospheric transmission bands. Our lasers produce a circular TEM00 Gaussian beam for superior performance.

Q-TUNE-G Series

Q-TUNE-IRThe Q-TUNE-G series is a highly advanced air-cooled, tunable wavelength laser. It offers hands-free, automated tuning from 680 to 2100 nm, delivering up to 12 mJ pulse energy in the near-IR range. With a <10 cm-¹ linewidth and up to 100 Hz pulse repetition rate, it’s ideal for photoacoustic imaging, non-linear spectroscopy, and more. The user-friendly GUI and microprocessor control ensure ease of use, while the water-free, air-cooled design optimizes performance. The Q-TUNE-G series sets a new standard in precision and efficiency for researchers across disciplines.

Q-TUNE-IR Series

Q-TUNE-IRThe Q-TUNE-IR series is the perfect high peak power, coherent DPSS light source for researchers with infrared spectroscopy applications. This series uses an Optical Parametric Oscillator (OPO) to produce a tunable wavelength of 1380–4500nm (<10 cm-1 linewidth), achieving > 15mJ of pulse energy at the peak of the tuning curve. The Q-TUNE-IR requires little maintenance, with all laser electronics integrated into the housing, including an air-cooling system, eliminating the need for chillers or large power supplies while providing a guaranteed > 2 G shot pump diode lifetime.

Q-TUNE Series

Q-TUNE-IR

The Q-TUNE series is a highly efficient, air-cooled, tunable wavelength laser, providing up to 8mJ, shorter than 5ns pulses at up to 100Hz, designed for temporally resolved spectroscopy, metrology, photo-acoustic imaging, and remote sensing applications. This laser uses an optical parametric oscillator (OPO) to produce a tunable wavelength range of 410-2300 nm with a linewidth narrower than 6 cm-1, which can extend to 210-410 nm with an optional second harmonic generator. Options for air purging for UV optics, spectrometer, and fiber-coupled OPO output are also available.

Q-SHIFT Series

Q-Shift SeriesThe Q-SHIFT series of Q-switched DPSS lasers is designed for researchers and application specialists working in micromachining, dermatology, LIDAR, time-resolved laser spectroscopy, and LIBS applications. With its built-in nonlinear wavelength conversion stage, this series can produce unconventional DPSS wavelengths: 1163, 1177, 1300, 1317, 1551 & 1571 nm. The optional harmonics generator can generate up to the 4th harmonic for each fundamental wavelength, providing even more versatility. This series can produce up to 40mJ/1W @ 1163nm with up to 100Hz repetition rate.

Q-Spark

Quantas-Q-SPARK-266: High energy, compact, nanosecond, DPSS laser

The Q-SPARK series is an air-cooled, diode-pumped, Q-switched laser designed for researchers and application specialists working with ablation, LIDAR, remote sensing, and LIBS applications. The laser produces sub-nanosecond or nanosecond pulses with peak power up to 20 MW and pulse energies up to 20 mJ, making it ideal for a wide range of applications. With a short pulse (<800 ps to <2 ns), compact air-cooled package, and innovative water-free laser crystal end-pumping technology, the Q-SPARK series delivers high-quality, low divergence, Gaussian-like laser beams.

Q1 Series

Quantas-Q1-211: High energy, compact, nanosecond, DPSS laser

The Q1 series is a compact, energy-efficient, diode pumped, air-cooled, Q-switched laser available with up to 35 mJ at 1064, 40 mJ at 1053nm, and rep rates up to 50Hz. The high peak powers and low divergence of the Q1 series enable efficient harmonic conversion through the 5th harmonic (213 or 211nm). The innovative design results in a user-friendly, turnkey system that requires little maintenance, and the laser’s variable pulse repetition rate and built-in sync pulse generator provide flexibility for triggering user equipment.

Q2 Series

Quantas Q2 QLI

The Q2 series is a diode-pumped, air-cooled, Q-switched laser emitting at 1064 or 1053nm, designed for a wide range of applications that require high peak power pulses. The water-free end-pumping technology produces high peak powers and low divergence, enabling efficient harmonics conversion through the 5th harmonic (213 or 211nm). This versatile platform can be configured in many ways, including up to 80mJ pulse energy at 10 Hz pulse repetition rate or up to 20mJ at 100 Hz. In the short cavity configuration, pulse duration can be reduced by 50% compared to the standard configuration.

Q2HE Series

Quantas-Q2HE-211: High energy, compact, nanosecond, DPSS laser

The Q2HE series is a highenergy, q-switched, DPSS laser series, available in either 1053nm or 1064nm fundamental wavelengths, with optional 2nd, 3rd, 4th, or 5th harmonic generation. This air-cooled series of lasers is designed for a wide range of applications that require high peak power pulses. Due to a short laser cavity, excellent thermal properties of the crystal, and an innovative water-free crystal cooling technology, the Q2HE series can deliver up to 120mJ of pulse energy and/or up to 4W average output power. This advanced laser design results in a compact, user-friendly turnkey system that requires little maintenance.  

R Series

R Series

The R series of wavelength-stabilized single-mode and multimode laser diodes offer narrow linewidth output in wavelengths from 633nm thru 1064nm, with output powers up to 5 W. This highly customizable series offers package options ranging from components as basic as a TO-56 or 14-pin BF packaged diodes to OEM modules, including electronics, to UL/CE and IEC-certified turn-key systems. The R series is the perfect source for various markets, including chemical analysis, bio-medical, fiber laser, and scientific applications.

REP Series

The REP series includes high-performance, tunable, single-frequency (DFB-like) diode lasers and Fabry-Perot laser diodes in wavelengths from 760nm thru 2350nm, designed to address challenges in Gas Sensing, LIDAR, Spectroscopy, and Telecom. The REP series includes high-power and narrow linewidth options, covering various product ranges at the most popular wavelengths, providing customizable units with multiple packaging options, including the Fiber coupled 14-pin butterfly, TO39 (w/TEC), and TO56.

RPK Series

The RPK Series of multiple, single-emitter fiber-coupled diode lasers are available in wavelengths from 405nm thru 1550nm with up to ≈ 500W output power. Our specialized fiber-coupling techniques ensure high efficiency, stability, and superior beam quality, while rigorous inspections and burn-in procedures guarantee each product’s reliability, stability, and long lifetime. Highly customizable packages allow us to meet our customers’ specific needs, providing high-quality products at reasonable prices. 

RPKBDL Series

The RPKBDL Series is a high-power direct diode turn-key system available in wavelengths of 445nm, 915nm, or 976nm, providing up to 3kW of power and unprecedented brightness. Its pluggable design makes maintenance easy, avoiding troubles and high time costs caused by return-to-factory maintenance. The RPKBDL series results from continuous innovation, ensuring high technical strength and product quality. This highly customizable system allows us to meet our customers’ specific needs, providing high-quality products at reasonable prices.

RWLD Series

The RWLD series offers competitively priced laser diodes with high beam quality and a wide variety of products to support multiple applications. Available in a wide range of wavelengths, power levels, and packages. The RWLD wavelength options span from 405nm to 1650nm, with output powers in the range of 10 mW to 300 mW, packaged in a TO-18 package with photodiode. We also offer customized options, such as a customized wavelength, output power, or a special package to meet your specific needs.

RWLP Series

R3Z0-WSLP-905-050m-M-PD: 905nm Multimode Fiber Coupled Laser Diode

The RWLP series offers an affordable and versatile solution for your laser application needs with single-mode and multimode options and wavelengths from 405nm thru the IR region. With customizable options, our team can work with you to solve any challenges you may face. Rigorously tested for long-term reliability, the RWLP series ensures consistent performance and high beam quality. Perfect for integration, this series supports multiple applications including biological and analytical instrumentation. 

Microchip Series

Bright Microlaser Microchip SB1 Laser

The Microchip series is a line of ultra-compact, single longitudinal mode (SLM), narrow linewidth, passive q-switch, ns/ps pulsed DPSS lasers. Offering exceptional performance and versatility in a compact form factor, every model is 1:1 interchangeable, regardless of wavelength. The lasers feature pulse widths from 400 ps to 2 ns, pulse energy up to 80 µJ, and repetition rates up to 100 kHz. Available in wavelengths from the UV to the NIR, this series is designed for LIDAR, 3D scanning, LIBS, night vision, and more.

SMX Series

image of several free-space and fiber-coupled laser diode package typesThe SMX Series of US-made, high-power, thermally stable, and cost-effective InP laser diodes is available at 1470, 1550, and 1940 nm, perfect for medical, military, aerospace, LIDAR, free-space communication, and more! With a patented EPI structure, low-cost packaging, ISO certified supply chain with full lifecycle traceability, focus on ease of integration, and custom design capabilities, this laser diode family is an excellent choice for reliable, high-power InP devices.

SOL Series

SOL-03-532: 532nm Nanosecond Laser

The SOL series is the most compact, air-cooled, Q-switched DPSS nanosecond laser available in the power range from 4W to 40W @ 1064nm. With its excellent beam quality, high peak power, wavelength options (10W and 650µJ at 532nm / 4W @ 355nm), and wide range of add-ons, this series is ideal for the most demanding industrial and scientific applications. With a rugged, compact, lightweight, and easy-to-use single-unit design, the SOL laser is easy to integrate into any system, providing superior operational flexibility and performance/cost ratio.

TG Series

R1Z5-TG420

The TG Series of laser diodes emit in the blue spectral range with non-standard wavelengths from 418 nm up to 466 nm, perfect for Life Science applications, with a typical output power of 50mW and an absolute maximum output power of 100mW. Assembled in a 5.6 mm (TO-56) packages the TG series is a suitable for a wide range of OEM applications that require blue/violet light, including ECDL with low AR coating option.

UniMir Series

mirSense UniMir HHLThe uniMir Series is a long-wavelength, single-frequency, DFB, CW Quantum Cascade Laser based on proprietary technology. The technology’s versatility allows them to address any wavelength between 10 and 18µm in CW and up to 21µm in pulsed mode. Now commercially available in a sealed High Heat Load (HHL) package, with integrated collimating lens, thermistor, and thermoelectric cooler (TEC), well suited for integration into systems, or as a stand-alone turnkey system for R&D and detection applications.

VaryDisk Series

The VaryDisk Series is a versatile family of thin-disk laser systems that provide high pulse energies at high average powers and are suitable for lab or industrial use. These thin-disk regenerative amplifiers offer a range of output specifications to fit various application needs. The base configurations provide 25 W average power with 2.5 mJ pulse energy @ 343 nm (THG), 50 W and 5 mJ @ 515 nm (SHG), and 100W and 100 mJ @ 1030 nm.

Vento Series

Vento-532-7: 532nm Picosecond DPSS Laser

The Vento series is a compact and ruggedized sub-nanosecond DPSS laser series designed for scientific and industrial applications such as precision LIDAR and materials processing. With pulse durations down to 500 ps and repetition rates up to 200 kHz, this laser series produces a high average power of up to 25 W @ 532 nm and up to 40 W @ 1064 nm. The Vento series has many options, from beam expanding and collimating optics to a low jitter option to extended operating temperature range, up to IP68 package, remote control cbox & software, and much more.

Wedge Series

Wedge-XF-1064: 1064nm Picosecond Laser

The Wedge series of DPSS lasers is designed for OEM applications such as micromachining, LIDAR, LIBS, and more. Based on proprietary fast Q-switching technology, this series is compact, sealed, and monolithic, making them insensitive to vibrations & harsh environments. High peak powers, relatively low energy and low heat generation allow efficient ablation and non-linear interaction. Available from 266-3106nm, up to 8 mJ pulse energy @ 1064, the compact and lightweight package benefits LIDAR and aerospace applications, while short pulses provide exact time-of-flight measurements.