PDT Lasers: Photodynamic Therapy Lasers

What are PDT Lasers?

Photodynamic therapy or PDT, refers to any use of modulated laser light, used in conjunction with a photosensitizing chemical substance to induce a therapeutic response. Among the advantages of Photodynamic therapy is lessening the need for delicate surgery and lengthy recuperation and minimal formation of scar tissue and disfigurement. PDT is widely considered to be minimally invasive and minimally toxic. Applications of PDT lasers vary widely from photoactivated medicines to cancer targeting photothermal nanoparticles, to near-infrared laser-induced vein dilation.

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PDT Applications

Cancer Treatment: Laser diodes are utilized in cancer treatment to selectively target and destroy cancer cells. The process involves administering a photosensitizing agent that accumulates in cancer cells. When activated by laser light, typically in the range of 630 to 800 nanometers, the photosensitizer generates reactive oxygen species that cause cell death. PDT can be used as a localized treatment for superficial cancers or in combination with other therapies for deeper tumors.

Dermatology: Laser diodes are employed in dermatology to treat various skin conditions, including precancerous lesions, acne, and certain types of skin cancers. The photosensitizer is applied topically or injected systemically, targeting the abnormal cells or lesions. Laser light in the range of 630 to 660 nanometers is then used to activate the photosensitizer, leading to cell destruction or targeted therapy. PDT in dermatology offers a non-invasive or minimally invasive approach with excellent cosmetic outcomes.

Ophthalmology: Laser diodes are used in ophthalmology to treat certain eye conditions, such as age-related macular degeneration (AMD). A photosensitizing agent is injected intravenously and selectively accumulates in abnormal blood vessels in the retina. Laser light in the range of 690 to 800 nanometers is then directed to the target area, activating the photosensitizer and causing closure or destruction of the abnormal vessels. PDT can help preserve vision and slow the progression of AMD.

Recommended Laser Series

We recommend the following laser series options for PDT applications. There can often be a ton of options and many variables. Contact us today for help finding the perfect laser for your specific application!

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HL Series

TG420

The HL Series offers versatile and high-quality laser diode products in a variety of wavelengths and high-power options, ideal for direct imaging, industrial, and bio/medical applications. These reliable, efficient, and compact diodes come in TO-Can packages, making them perfect for OEM integration. Additionally, they operate with TE mode oscillation and are RoHS compliant, ensuring safe use. Choose the HL Series for quality, reliability, and performance in laser diodes.

JDL Series

The JDL series of high-power laser bars are industry-leading and designed for a variety of optical pumping and DDL applications in materials processing, medicine, and sensing. Our unmounted laser bars offer a wide range of emitter configurations, cavity lengths, and operational modes up to 500 W. Our diode laser stacks can scale power into the multikilowatt range. We focus on delivering the highest-quality laser solutions with a commitment to reducing cost of ownership for our customers.

JOLD-FC Series

The JOLD-FC series of high-power diode lasers and fiber-coupled modules are fully customizable and available at various levels of integration, providing a cost-effective solution for OEM applications. With superior reliability and electro-optical efficiency, our lasers offer industry-leading performance. Our commitment to quality is reflected in our clearly defined production processes and certifications, which ensure that our solutions are both precise and productive, while minimizing waste and risks.

We offer standard wavelengths of 808 nm, 940 nm and 980 nm. The fiber core diameter of our diode lasers is 200 µm, 400 µm or 600 µm. On request, we will be happy to adapt the parameters to your individual requirements. You can also choose between pilot lasers, monitor diodes and integrated Peltier elements.

JOLD-Open Heatsinks Series

The JOLD-Open Heatsinks Series offers industry-leading performance for mounted diode lasers. Our proprietary heat sink and assembly technology, paired with our focus on advanced optical pumping and direct-diode-laser technology, results in diode lasers with unmatched performance. We’ve pioneered high-power diode laser assembly in high-volume manufacturing and tailored our laser bars to specific heat sink technology and operating modes. With reliable, cost-effective solutions, JOLD-Open Heatsinks is the clear choice for diode laser technology.

JOLD-Stacks Series

The JOLD–Stacks Series offers a highly modular approach for power scaling well into the kW-range through vertical stacking of individual sub-mounts within multi-laser-bar packages. Our optimized beam quality (BPP) is achieved through our unique approach of reducing the pitch of neighboring stacks without compromising cooling capacity. Our proven hard-solder technology and strictly monitored production processes ensure tried & tested reliability under even the harshest environmental conditions. The series also features microchannel-cooled packages for CW-operation, actively cooled with deionized (DI) water.

LDX Series

The LDX Series of made-in-the-US, high-power, multimode laser diodes provide wavelengths from 400nm – 1900nm, a wide range of output powers and package types, as well as completely customized solutions. We have been offering these high-quality laser diodes for over 25 years. The performance, reliability, and lifetimes are time tested, and if for some reason there is an issue, we will make it right.

RPK Series

The RPK Series of multiple, single-emitter fiber-coupled diode lasers are available in wavelengths from 405nm thru 1550nm with up to 300W output power. Our specialized fiber-coupling techniques ensure high efficiency, stability, and superior beam quality, while rigorous inspections and burn-in procedures guarantee each product’s reliability, stability, and long lifetime. Highly customizable packages allow us to meet our customers’ specific needs, providing high-quality products at reasonable prices.

RWLD Series

The RWLD series offers competitively priced laser diodes with high beam quality and a wide variety of products to support multiple applications. Available in a wide range of wavelengths, power levels, and packages. The RWLD wavelength options span from 405nm to 1650nm, with output powers in the range of 10 mW to 300 mW, packaged in a TO-18 package with photodiode. We also offer customized options, such as a customized wavelength, output power, or a special package to meet your specific needs.

RWLP Series

The RWLP series offers an affordable and versatile solution for your laser application needs with single-mode and multimode options and wavelengths from 405nm thru the IR region. With customizable options, our team can work with you to solve any challenges you may face. Rigorously tested for long-term reliability, the RWLP series ensures consistent performance and high beam quality. Perfect for integration, this series supports multiple applications including biological and analytical instrumentation.

SMX Series

The SMX Series is a high-power, thermally stable, and cost-effective line of InP laser diodes, available with wavelengths centered around 1470, 1550, and 1940 nm, perfect for medical, military, aerospace, LIDAR, free-space communication, and more! With a patented EPI structure, low-cost packaging, ISO certified supply chain with full lifecycle traceability, focus on ease of integration, and custom design capabilities, this laser diode family is an excellent choice for reliable, high-power InP devices.