Research & Biophotonics Lasers – Lasers for Research & Biophotonics Markets

What are Reasearch & Biophotonics Lasers?

Research & Biophotonics Lasers play a crucial role in the field of scientific research and biophotonics, providing scientists and researchers with powerful tools to investigate, analyze, and manipulate various aspects of light-matter interactions. These advanced laser systems offer precise control and high energy output, enabling a wide range of applications in imaging, spectroscopy, molecular analysis, and more. By harnessing the unique properties of laser light, researchers can delve into the mysteries of the microscopic world, unravel complex biological processes, and uncover valuable insights that contribute to advancements in various scientific disciplines.

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As research and the biosciences have evolved and diversified over the past 50 years so have the laser application and technologies used within it.  Because of their early adoption of laser technology, the medical, biomedical, and life sciences have made rapid progress, including the complete mapping of the human genome.

On the research side of things, the most popular life science laser application is fluorescence.  Fluorescence has become so popular that it has been subdivided into a wide range of different applications, each leading to their own field of study.  This includes but is not limited to flow cytometry, DNA sequencing, confocal fluorescence microscopy, and fluorescence lifetime imaging microscopy.  More recently ultra-fast lasers have become more prevalent in fluorescence microscopy enabling multiphoton excitation allowing users to create high-resolution fluorescence images of living cells, without damaging the cells in the process.


To learn more about the various research & biophotonics laser applications and the recommended laser sources, click on any of the application groups listed below, or click the ‘Get Answers’ button to contact us for quick support and answers to your questions!

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Research & Biophotonics Laser Applications

Here are some of the key applications we support in the Research & Biophotonics Markets – Click an Application Group to learn more:

Imaging & Analysis
  • Fluorescence Lifetime
  • Maldi-ToF
  • Particle Image Velocimetry (PIV)
Spectroscopy & Analysis
  • Laser Induced Breakdown Spectroscopy (LIBS)
  • Non-linear Spectroscopy
  • Raman Spectroscopy
Measurement & Analysis
  • Dynamic Light Scattering
  • Infrared Absorption Spectroscopy
  • Laser Doppler Velocimetry
  • DIAL LIDAR
  • Photoluminescence
Molecular Manipulation & Analysis
  • Confocal Fluorescence Microscopy
  • DNA Sequencing
  • Flow Cytometry
  • Optogenetics
Pump Lasers
  • Pump Lasers – Fiber & DPSS
Seed Lasers
  • Seed Lasers – Fiber & DPSS
Optical Amplifiers
  • Fiber & DPSS

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Matchbox Series

R1Z4-Matchbox Laser

The Matchbox series offers excellent performance and reliability in the “World’s Smallest” ultra-compact, all-in-one, integrated laser head. They can operate on a 5V power supply while maintaining low noise operation. The monolithic design of the Matchbox Series laser includes thermally stabilized optics in a hermetically sealed housing, ensuring reliable and maintenance-free operation. This series is available in wavelengths from 405 nm thru 1064nm, with options for collimated beam or fiber-coupled output, and single-mode and multimode versions.

Skylark Series

The Skylark series of ultrareliable, high performance, CW single-frequency lasers are available at a variety of wavelengths with high average powers, making them well suited for a variety of highly specialized scientific and industrial applications. BRaMMS Technology® enables superior performance, high output powers, and outstanding beam properties in an overall compact footprint. The Skylark series of lasers are utilized in a range of applications including holography, metrology, spectroscopy, and quantum technology.

CEUV Series

R0Z2-Image-Compact-Efficient-UV-LaserThe CEUV series is a commercial line of compact and efficient DPSS laser sources, capable of operating over a wide range of pulsing conditions (duty-cycle and PRF), in a low SWaP package, with average power up to ≈5W @ 266nm, 10W @ 355nm or 532nm, 20W @ 1064nm. This series of DPSS lasers provides a combination of compact, efficient, and high-power performance in a rugged design suitable for harsh environments and airborne applications. The design has been tested in brassboard hardware and a prototype is being developed.

LGK Series

The LGK series of HeNe laser modules boast an excellent TEM00 beam, robust mechanical design, a long service life of up to 30,000 hours, and are available in 543nm, 594nm, and 632.8nm wavelengths, with output powers up to 20mW. Choose between standard and customized models, with options for single or multimode, random or linear polarization, Brewster window tubes, and fiber coupling. Designed for long life, low noise, and high stability, with many customization options, these HeNe lasers are perfect for applications including spectroscopy, interferometry, holography, medical, and more! 

HL Series

TG420

The HL Series offers versatile and high-quality laser diode products in a variety of wavelengths and high-power options, ideal for direct imaging, industrial, and bio/medical applications. These reliable, efficient, and compact diodes come in TO-Can packages, making them perfect for OEM integration. Additionally, they operate with TE mode oscillation and are RoHS compliant, ensuring safe use. Choose the HL Series for quality, reliability, and performance in laser diodes. 

LaserBoxx Low Noise Series

The LaserBoxx Low Noise series of CW diode laser modules, with a variety of wavelengths from 375 to 785nm and output powers up to 350mW, offers highly customizable laser solutions for OEM and plug & play modules. With advanced features such as excellent beam quality, stability, and modulation capabilities, our lasers provide ultra-low noise and a wide range of options for SM, MM, and PM fiber coupling. Our dedicated control software, USB and RS232 interfaces, and external controller with power display make integration, operation, and remote diagnostics a breeze. Additionally, our rugged and compact design and wide variety of standard wavelengths ensure that our lasers can meet your specific needs. 

LaserBoxx HPE Series

LBX-488

The LaserBoxx HPE Series is a highly versatile and customizable laser module series that offers superior performance and reliability in a compact, driver integrated laser head. With a wide range of wavelengths from the UV to the NIR, this series offers high-power laser diode modules that are perfect for a variety of applications. The LaserBoxx HPE series also includes removable multimode fiber coupling options and dedicated control software with USB and RS232 interfaces, as well as an external controller with power display, ensuring easy integration and precise power and modulation control. 

LaserBoxx SLM Series

The LaserBoxx-SLM series are single longitudinal mode (SLM) CW diode laser modules available in green, yellow, red, and NIR wavelengths, delivering ultra-narrow linewidths, with excellent temperature stability and low noise current. Embedded firmware locks the laser on the same mode at each startup. This customizable, compact, self-contained laser module is available in turn-key or OEM versions and utilizes a proprietary alignment-free, monolithic resonator, and comes standard with a graphic user interface with remote diagnostics via USB, RS232, or direct I/O interface. With modulation capabilities and adjustable power options, the SLM Series is versatile and adaptable to a wide range of applications.

LDX Series

The LDX Series of made-in-the-US, high-power, multimode laser diodes provide wavelengths from 400nm – 1900nm, a wide range of output powers and package types, as well as completely customized solutions. We have been offering these high-quality laser diodes for over 25 years. The performance, reliability, and lifetimes are time tested, and if for some reason there is an issue, we will make it right. 

LGR Series

The LGR series of HeNe laser replacement tubes provide unparalleled performance for a wide range of applications. have a robust mechanical design, excellent beam quality, and a long service life of up to 30,000 hours. Standard and customized models are available in a large variety in the red, green, and yellow spectral ranges with output powers up to 20 mW. Options for singlemode or multimode, random or linear polarization, and Brewster window tubes for educational and scientific purposes. 

LXCc Series

R2Z3-L4Cc Combiner

The LXCc series is a range of compact, highly customizable, and flexible all-in-one laser combiners that provide the widest variety of wavelength options, up to 7 different laser lines (up to 500 mW output power per line), direct modulation on every source, SLM capabilities, proven long-term stability, and many other advanced features. The turnkey or OEM versions allow a large choice of lasers from 375nm up to 1064nm. The extension module provides the ultimate level of flexibility with options for up to 4 optical fiber outputs, AOTF modulator, motorized ND filter, integrated fast switching output ports for FRAP, or adjustable split power for light-sheet microscopy. 

MicroMake Series

MicroMake: Micromachining Laser SystemMicroMake Series from Bright System is an integrated compact laser micromachining system for high precision and resolution applications such as ablation and cutting of programmable arbitrary shapes. The sub-nanosecond MicroMake series is a flexible platform capable of >35kW of peak power and processing speeds up to 40mm/second. The system includes all the needed devices for direct laser micro-processing in a single monolithic air-cooled configuration. Live microscope imaging of the sample is offered during all process phases for alignment and immediate quality check. All these features perfectly suit a large variety of materials utilized in the fields of microelectronic circuits, displays fabrication and correction, biomedical device machining and optical substrates microprocessing.

Nps Series

Nps-1064-10

The NPS series of ultrafast lasers is the ultimate solution for OEM integrators and researchers working with nonlinear optics applications like OPO pumping and narrowband Raman spectroscopy. The NPS series boasts remarkable features such as up to 10W average output power, <7ps pulse width, and a 40MHz repetition rate. The transform-limited operation, with a spectral width of <0.3nm, and accurate central wavelengths make these lasers a suitable candidate for highly efficient amplification by Nd-doped DPSS amplifiers.

Onda Series

Onda 532nm: 532nm High Energy Laser

The Onda series is a DPSS nanosecond OEM laser platform designed for high-end applications requiring excellent beam quality and high peak power in materials such as metals, glass, plastics, and various delicate and hard materials. This compact and easy to use laser series is available in wavelengths of 266, 355, 532, and 1064nm, with an extended operating temperature range and superior performance to cost ratio. The Onda seriesinternal optical layout and accurate temperature management enable high output energies without compromising the lifetime of the THG and FHG stages. 

One Series

One-1030-100: 1030nm Miniature Q-Switched Laser

The One Series is a versatile, passively q-switched laser series designed specifically for OEM integrators and application specialists working with industrial and portable applications like materials processing and airborne LIDAR. With its compact size and ability to operate at a fundamental wavelength of 1030nm, this series offers exceptional performance for a range of applications. The One Series can be configured in a fixed operational rep rate configuration, or an externally triggerable configuration. Available in both high energy configurations (up to 100uJ) and high average power configurations (up to 3W), the One series is a reliable choice for any application. 

PowerMir Series

mirSense Product Family

The PowerMir series is a line of high-power pulsed Quantum Cascade Lasers (QCL) based on our proprietary technology. Various integration levels available, including plug-and-play benchtop turnkey systems, OEM driver + laser modules, or just the HHL-packaged lasers. QCW operation allows for increased wall-plug efficiency and thermal dissipation. The PowerMir series incorporates high-powered diodes emitting in the main transmission bands of the atmosphere and offers ITAR-free technology. The TEM00 Gaussian beam allows for high-quality performance, and the user-friendly Windows software streamlines operation. 

Q-TUNE-G Series

Q-TUNE-IRThe Q-TUNE-G series is a highly advanced air-cooled, tunable wavelength laser with seamless OPO integration. It offers hands-free, automated tuning from 680 to 2100 nm, delivering up to 12 mJ pulse energy in the near-IR range. With a <10 cm-¹ linewidth and up to 100 Hz pulse repetition rate, it’s ideal for photoacoustic imaging, non-linear spectroscopy, and more. The user-friendly web interface and microprocessor control ensure ease of use, while the water-free, air-cooled pump laser design optimizes performance. The Q-TUNE-G series sets a new standard in precision and efficiency for researchers across disciplines.

Q-TUNE-IR Series

Q-TUNE-IRThe Q-TUNE-IR series is the perfect high peak power, coherent, DPSS light source for researchers working with infrared spectroscopy applications. This series uses an Optical Parametric Oscillator (OPO) to produce tunable wavelength in the 1380 – 4500 nm range with a linewidth less than 10 cm-1, achieving > 6.5mJ of pulse energy @ 3500nm for the F-10 configuration (> 2mJ @ 3500nm for C-10) with a 10Hz repetition rate. The Q-TUNE-IR requires little maintenance, with all laser electronics integrated into the housing, including an air-cooling system, eliminating the need for chillers or large power supplies, all while providing a guaranteed pump diode lifetime greater than 2 giga-shots. 

Q-TUNE Series

Q-TUNE-IR

The Q-TUNE series is a highly efficient, tunable wavelength laser designed for researchers working with temporally resolved spectroscopy, metrology, photo-acoustic imaging, and remote sensing applications. This laser uses an optical parametric oscillator (OPO) to produce a tunable wavelength range of 410-2300 nm with a linewidth narrower than 6 cm-1, which can be extended to 210-410 nm with an optional second harmonic generator. With a pulse duration shorter than 5ns and an upper repetition rate of 100Hz, the Q-TUNE series provides a perfect coherent light source for precise scientific measurements. 

Q-SHIFT Series

Q-Shift SeriesThe Q-SHIFT series of Q-switched DPSS lasers is designed for researchers and application specialists working in micromachining, dermatology, LIDAR, time-resolved laser spectroscopy, and LIBS applications. With its built-in nonlinear wavelength conversion stage, this series allows the production of unconventional fundamental DPSS wavelengths, including 1163, 1177, 1300, 1317, 1551 and 1571 nm options, making it an ideal choice for those seeking wavelengths that are not accessible with conventional solid-state laser sources. With the optional harmonics generator, it is possible to generate up to the 4th harmonic for each fundamental wavelength, providing even more versatility. 

Q-Spark

Quantas-Q-SPARK-266: High energy, compact, nanosecond, DPSS laser

The Q-SPARK series is an air-cooled, diode-pumped, Q-switched laser designed for researchers and application specialists working with ablation, LIDAR, remote sensing, and LIBS applications. The laser produces sub-nanosecond or nanosecond pulses with peak power up to 20 MW and pulse energies up to 10 mJ, making it ideal for a wide range of applications. With a short <1.5 ns pulse, compact air-cooled package, and innovative water-free laser crystal end-pumping technology, the Q-SPARK series delivers high-quality, low divergence, Gaussian-like laser beams.

Q1 Series

Quantas-Q1-211: High energy, compact, nanosecond, DPSS laser

The Q1 series is a compact, energy-efficient, diode pumped, air-cooled, Q-switched laser available at 1064 and 1053nm with up to 45 mJ of pulse energy and rep rates up to 50Hz. The high peak powers and low divergence of the Q1 series enable efficient harmonic conversion through the 5th harmonic (213 or 211nm). The innovative design results in a user-friendly, turnkey system that requires little maintenance, and the laser’s variable pulse repetition rate and built-in sync pulse generator provide flexibility for triggering user equipment. 

Q2 Series

Quantas Q2 QLI

The Q2 series is a diode-pumped, fully air-cooled, Q-switched laser designed for a wide range of applications that require high peak power pulses. Its innovative water-free laser crystal end-pumping technology produces Gaussian-like, low divergence laser beams with high peak powers, allowing for efficient harmonics conversion through the 5th harmonic. This versatile platform can be configured in many ways, including up to 80mJ pulse energy at 10 Hz pulse repetition rate or up to 20mJ at 100 Hz. The laser can emit either 1053 nm or 1064 nm wavelength, and in the short cavity configuration, pulse duration can be reduced by 50% in comparison to standard configuration. 

Q2HE Series

Quantas-Q2HE-211: High energy, compact, nanosecond, DPSS laser

The Q2HE series is a highenergy, q-switched, diode-pumped solid-state (DPSS) laser series, available in either 1053nm or 1064nm fundamental wavelengths, with optional 2nd, 3rd, 4th, or 5th harmonic generation. This air-cooled series of lasers is designed for a wide range of applications that require high peak power pulses. Due to a short laser cavity, excellent thermal properties of the crystal, and an innovative water-free crystal cooling technology, the Q2HE series can deliver up to 120mJ of pulse energy and/or up to 4W average output power. This advanced laser design results in a compact, user-friendly turnkey system that requires little maintenance.  

R Series

R Series

The R series of wavelength stabilized singlemode and multimode laser diodes offer narrow linewidth output in wavelengths from 633nm thru 1064nm. This highly customizable series offers package options ranging from components as basic as a TO-56 or 14-pin BF packaged diodes, to OEM modules including electronics, to UL/CE and IEC certified turn-key systems. The R series is the perfect source for various markets, including chemical analysis, bio-medical, fiber laser, and scientific applications. 

REP Series

The REP series includes high-performance, tunable, single-frequency (DFB-like) diode lasers and Fabry-Perot laser diodes in wavelengths from 1270nm thru 2350nm, designed to address challenges in Gas Sensing, LIDAR, Spectroscopy, and Telecom. The REP series includes high-power and narrow linewidth options, covering various product ranges at the most popular wavelengths, providing customizable units with multiple packaging options, including the Fiber coupled 14-pin butterfly, TO39 (w/TEC), and TO56. For a complete module incorporating the fiber-coupled butterfly package with an integrated current driver and TEC controller, designed for ease of operation, it is the ideal platform for high stability gas detection or remote sensing.  See the DX1 Series.

RHAML Series

The RHAML series of diode laser modules deliver a uniform, stable output beam that crucual for machine vision applcations, especially in 3D vision systems. The compact, RHAML series is a reliable light source that incoroporates a fucusing lens that can be easily adjusted by the user. Additionally, the RHAML series is fully IP67 compliant, making it an ideal solution for use in harsh environmental conditions and production/industrial facilities.

RML Series

The RML series of laser diode modules are available with single mode fiber outputs with a set wavelength from 405nm – 2500nm. The compact RML series is available with up to 80mW of output power in a package measuring 15mm in diameter and 40mm in length (without connector) . As an option these modules are offered with a potentiometer for power adjustment, external TTL modulation up to 1MHz and analog modulation up to 100kHz.

RPK Series

The RPK Series of multiple, single-emitter fiber-coupled diode lasers are available in wavelengths from 405nm thru 1550nm with up to 300W output power. Our specialized fiber-coupling techniques ensure high efficiency, stability, and superior beam quality, while rigorous inspections and burn-in procedures guarantee each product’s reliability, stability, and long lifetime. Highly customizable packages allow us to meet our customers’ specific needs, providing high-quality products at reasonable prices. 

RWLD Series

The RWLD series offers competitively priced laser diodes with high beam quality and a wide variety of products to support multiple applications. Available in a wide range of wavelengths, power levels, and packages. The RWLD wavelength options span from 405nm to 1650nm, with output powers in the range of 10 mW to 300 mW, packaged in a TO-18 package with photodiode. We also offer customized options, such as a customized wavelength, output power, or a special package to meet your specific needs.

RWLP Series

R3Z0-WSLP-905-050m-M-PD: 905nm Multimode Fiber Coupled Laser Diode

The RWLP series offers an affordable and versatile solution for your laser application needs with single-mode and multimode options and wavelengths from 405nm thru the IR region. With customizable options, our team can work with you to solve any challenges you may face. Rigorously tested for long-term reliability, the RWLP series ensures consistent performance and high beam quality. Perfect for integration, this series supports multiple applications including biological and analytical instrumentation. 

Microchip Series

Bright Microlaser Microchip SB1 Laser

The Microchip series is a line of ultra-compact, passively q-switched, single longitudinal mode (SLM), narrow linewidth, DPSS lasers that offer exceptional performance in a compact form factor. The lasers feature pulse durations ranging from 400 ps to 2 ns, energy levels up to 80 µJ, and repetition rates up to 100 kHz. Available in wavelengths from the UV to the NIR, this series is designed for OEM integrators and researchers working with LIDAR, 3D scanning, LIBS, night vision, and more. The lasers offer both nanosecond and picosecond options and are interchangeable with the same form factor and electrical and software interfaces across wavelengths, making them a flexible and versatile solution. 

SMX Series

image of several free-space and fiber-coupled laser diode package typesThe SMX Series is a high-power, thermally stable, and cost-effective line of InP laser diodes, available with wavelengths centered around 1470, 1550, and 1940 nm, perfect for medical, military, aerospace, LIDAR, free-space communication, and more! With a patented EPI structure, low-cost packaging, ISO certified supply chain with full lifecycle traceability, focus on ease of integration, and custom design capabilities, this laser diode family is an excellent choice for reliable, high-power InP devices.

SOL Series

SOL-03-532: 532nm Nanosecond Laser

The SOL series is the most compact, air-cooled, Q-switched DPSS nanosecond laser available in the power range from 4W to 40W @ 1064nm. Available @ 1064nm, 532nm, and 355nm, the SOL laser series offers excellent beam quality and high peak power, capable of up to 10W and 650µJ at 532nm and 4W @ 355nm, making it the ideal source for the most demanding industrial and scientific applications. With a rugged, compact, lightweight, and easy to use single unit design, the SOL laser is easy to integrate into micro-machining and marking applications, providing superior operational flexibility and performance/cost ratio. 

TG Series

R1Z5-TG420

The TG Series of laser diodes emit in the blue spectral range with non-standard wavelengths from 418 nm up to 466 nm, perfect for Life Science applications, with a typical output power of 50mW and an absolute maximum output power of 100mW. Assembled in a 5.6 mm (TO-56) packages the TG series is a suitable for a wide range of OEM applications that require blue/violet light, including ECDL with low AR coating option.

UniMir Series

mirSense UniMir HHLThe uniMir Series is a long-wavelength, single-frequency, DFB, CW Quantum Cascade Laser based on proprietary technology. The technology’s versatility allows them to address any wavelength between 10 and 18µm in CW and up to 21µm in pulsed mode. now commercially available in a sealed High Heat Load (HHL) package, with integrated collimating lens, thermistor, and thermoelectric cooler (TEC), well suited for integration into systems, or as a stand-alone turnkey system for R&D and detection applications.

VaryDisk Series

VaryDisk E150The VaryDisk Series is a versatile and fully functional family of thin disk laser systems, providing high pulse energies at high average powers, suitable for laboratory investigations or industrial use. These thin disk regenerative amplifiers provide a range of beam parameters, depending on the configuration and your specific application needs. With a range of output specifications to choose from, including multiple seed lasers, customers can select the ideal configuration to meet their needs with many customization options available. The base configurations offer options for pulse widths in the fs, ps, and ns range, up to 1000 W average power, up to 150 mJ pulse energy, 1 kHz to 125 kHz rep. rate, and 1030 nm, 515 nm (SHG), and 343 nm (THG) wavelength options.

Vento Series

Vento-532-7: 532nm Picosecond DPSS Laser

The Vento series is a compact and ruggedized sub-nanosecond DPSS laser series designed for OEM integrators, application specialists, and researchers working with scientific and industrial applications such as precision LIDAR and materials processing. With pulse durations down to 500 ps and repetition rates up to 200 kHz, this laser series produces high average power of up to 25 W @ 532 nm and up to 40 W @ 1064 nm. The Vento series features beam expanding and collimating optics, low jitter option, extended operating temperature range, pulse energy modulation up to IP68 Package, circular polarization, remote control cbox and software interface, air and water-cooled options, and AC-DC power supply. 

Wedge Series

Wedge-XF-1064: 1064nm Picosecond Laser

The Wedge series is a line of DPSS lasers designed specifically for OEM applications such as micro machining of hard and soft materials, specialty marking, glass and crystal engraving, LIDAR, LIBS, spectroscopy, and medical diagnostics. These diodepumped lasers, based on proprietary fast Q-switching technology, are compact, sealed, and monolithic which makes them insensitive to vibrations and harsh environments. With high peak powers and relatively low energy and heat generation, they allow efficient ablation and non-linear interaction with most materials. The compact and lightweight package is a great benefit in LIDAR and other aerospace applications, while short pulses provide extremely precise time-of-flight measurements.